Andreas Lüthi is a research group leader at the FMI and Professor at the University of Basel. He is an expert in the physiological and behavioural analysis of amygdala function. He has pioneered in vivo electrophysiological methods to study amygdala function in behaving mice. He has a long-standing track record in the field of synaptic plasticity and learning.
The Friedrich Miescher Institute for Biomedical Research (FMI) in Basel, Switzerland is one of the leading biomedical research centres in Europe. Research at FMI focuses on the fields of epigenetics, growth control and neurobiology. FMI maintains a wide range of technical platforms including functional genomics and proteomics, in vivo confocal microscopy, and an extensive animal facility for behavioural experiments. FMI’s Department of Neuroscience consists of 8 research groups with more than 70 researchers focusing on the assembly and function of neuronal circuits with the goal to connect modifications in structural and functional circuit properties as a consequence of genetic factors, experience, and/or disease processes to biomedically relevant behavioural changes. Neuroscience groups at FMI are organizing a bi-annual EMBO-FMI Conference series, which is recognized as the major international forum for neuronal circuit research.
Main Tasks in this Project: The main task of this project partner is the in depth analysis of synaptopathy models using high-end in vitro/in vivo electrophysiological and behavioural techniques. The group has an extensive track record in the analysis of synaptic plasticity and neuronal circuits in the amygdala in the context of fear conditioning and extinction using in vitro and in vivo electrophysiological and imaging approaches